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They are: Naltrexone , a medication that blocks opioid receptors and has long been used in the treatment of alcohol and opioid dependence

For more context on how GLP-1s change appetite and digestion, read our guide on how GLP-1 works for weight loss

People monitoring effects often track IGF-1 and, if relevant, fasting glucose

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The hormone also slows down gastric emptying and digestion, which helps us feel physically fuller for longer periods of time. Delayed stomach emptying also prevents blood glucose spikes, per the Cleveland Clinic