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The evidence balance on compounded GLP-1 safety The National Center for Complementary and Integrative Health (NCCIH), the FDA, and multiple medical societies - including the American Diabetes Association - have published guidance noting that compounded GLP-1 preparations carry additional safety uncertainty compared to FDA-approved finished products
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The peptide's proven clinical efficacy across diabetes, obesity, and cardiovascular indications provides strong foundation for investigating novel therapeutic applications in neurodegeneration, kidney disease, and metabolic dysfunction
Animal-model studies have explored its effects on ischemia-reperfusion injury, fistula healing, and angiogenic vessel formation in chronic wound preparations