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You have three administration options: Option A: Injectable GHK-Cu only 200 to 600 mcg per day, subcutaneous Best for systemic tissue support (skin, joints, hair, internal tissues) No fasting required Option B: Topical GHK-Cu only Applied to target areas once or twice daily Best for localized skin concerns (face, abdomen, specific areas of laxity) Lower cost, no injection required Option C: Injectable plus topical (recommended for maximum benefit) Injectable for systemic support plus topical for targeted skin areas Most thorough approach Addresses both internal tissue health and external skin quality Step 4: Improve and Maintain As semaglutide is titrated up over the following months, continue GHK-Cu consistently

the longer-duration outcomes record remains concentrated at 2.4 mg and below

Ethics statement The project was approved by the Research Ethics Committee of the Institute of Health Sciences of the university (registration no

4 : 743749 Sato N, Iwata S, Nakamura K, Hori T, Mori K and Yodoi J (1995) Thiol-mediated redox regulation of apoptosis

10.1038/sigtrans.2017.23 63 LiuS.JinX.GeY.DongJ.LiuX.PeiX.et al (2025)

It is composed of: Adenosylcobalamin 2mg Methylcobalamin 2mg Hydroxocobalamin 1mg Water for Injection up to 5ml Vitamin B12 injections and infusions are indicated for use in those with low Vitamin B12 levels, or B12 deficiency