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70 This evolutionary dynamic has been demonstrated in NSCLC and melanoma treated with PD-1 blockade and explains why tumors with high mutational burden may still acquire rapid resistance to immunotherapy
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Pre-treatment of rats with 120 g/kg DSIP 20 minutes prior to subjection to hypoxia completely inhibited these hypoxia-induced reductions in mitochondrial respiratory activity
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Dssing M, Arlien-Sborg P, Petersen L, Ranek L
