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Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

Comparison of glycation of glutathione S-transferase by methylglyoxal, glucose or fructose [PMID: 21625951] Laboratory literature summary: Comparison of glycation of glutathione S-transferase by methylglyoxal, glucose or fructose

But if our body does not produce it, how can we get it

Rare reactions: Severe allergic responses, including anaphylaxis, are extremely uncommon

Alcohol is a depressant