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Additionally, in this group, a linear relationship existed between the observed change in CNFD and the change in symptoms for the ARA 290 subjects as assessed by PainDetect (Figure 6)

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Reduction of the SASP Inflammatory Cascade The Senescence-Associated Secretory Phenotype (SASP) involves the secretion of pro-inflammatory cytokines, growth factors, and proteases that damage neighboring cells

Werder EJ, Engel LS, Curry MD, Sandler DP (2020) Selenium modifies associations between multiple metals and neurologic symptoms in Gulf States residents