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doi: 10.1016/S0002-9440(10)65616-7 380 WendelnA
Of note, significant effects of GLP-2 and GLP-1 on hepatic regeneration have been described in rodent models of partial hepatectomy, suggesting a pro-regenerative role of GLP-2 10 , whereas GLP-1 seems to deteriorate post-hepatectomy liver regeneration 11
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This may be due to preserved endogenous GLP-1 activity, lower baseline insulin resistance, or PD-related hypothalamic dysfunction affecting appetite signaling
