(2) Aoyama K, Nakaki T
3.2 Immune cell death regulation ferroptosis 3.2.1 Influence of immune microenvironment on ferroptosis Immune microenvironment (TME) plays a key role in the development of tumor, and it can regulate the ferroptosis of tumor cells in many ways
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This is one of the most efficient energy-producing pathways in cells, therefore, high energy demanding tissues, such as heart and kidney, mainly rely on fatty acids utilization (Console et al., 2020)
Similarly, in Jurkat cells, X(PC) induced both apoptosis and a small degree of lytic death, again in the absence of caspase-1, reinforcing its broader substrate reactivity (Extended Data Fig