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doi: 10.1016/S0140-6736(21)00213-0 100 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

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Short cycles: Others employ DSIP in short-term cycles (e.g., 24 weeks) to avoid potential tolerance or adaptation

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Use different injection sites for different compounds

It is impossible to tell if the mTOR suppression and oxidative phosphorylation down-regulation occurred in neurons, astrocytes, or microglia