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Yao XQ, Hamelberg D (2019) Detecting functional dynamics in proteins with comparative perturbed-ensembles analysis

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This is particularly useful when endoscopy does not reveal evidence of inflammation or mucosal changes such as Barretts esophagus

Reapply every 23 hours, especially after sweating, swimming, or towel-drying

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It may also be considered by individuals who are sensitive to medications in general or those who are just starting their titration and want a gentler introduction