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A., Servan-Schreiber, D., Panchalingam, K., and McClure, R
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Dihexa did not alter aminoglycoside entry into hair cells but attenuated cell death through HGF-dependent intracellular signaling, with downstream contributions from the Akt, mTOR, and MEK pathways
The 2010s introduced gene-expression analysis: data generated through the Broad Institute's Connectivity Map indicated that GHK exposure modulated expression of 4,192 of the 13,424 human genes assayed, with approximately equal up- and down-regulation across stress-response, inflammation, and tissue-repair pathways [2]