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Vitamin B12 is found naturally in animal products such as meat, fish, eggs, milk, and poultry

Intramuscular administration of vitamin B12 is often preferred for its rapid improvement in patients with severe deficiency or severe neurological symptoms

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Inadequate initial treatment may result in suboptimal responses and persistent symptoms

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5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia