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Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)
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Seleno-GPx Mimicking Compounds as Radio-Modulatory Agents Over the years, antioxidant enzymes have gained importance as therapeutic agents for the treatment of oxidative stress-related disorders [68]
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