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liraglutide 3 mg (Saxenda), tirzepatide (Mounjaro)
The active comparator weakens a dieting-only explanation but does not prove receptor causality
These medications have made headlines because they are also highly effective when prescribed off-label for weight loss, helping people lose up to 20% of their body weight (or more, in some cases)
Tirzepatide Sometimes referred to as a dual-agonist because of its action beyond the GLP-1 receptor, tirzepatide is sold as Zepbound (approved for weight management) and Mounjaro (approved for diabetes)
Int J Mol Sci
US$ 28.00
US$ 23.63
US$ 23.70
