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For the first 12 months of availability, the mean monthly growth of GLP-1 RA exceeded 85% and reached 200% for certain GLP-1 RA medications [5]
Absolute contraindications to GLP-1 receptor agonists include: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 Previous serious hypersensitivity reaction to the specific GLP-1 drug Pregnancy and breastfeeding (for medications approved for weight management: Wegovy, Saxenda, and Zepbound) Patients should maintain age-appropriate cancer screening regardless of GLP-1 use
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JAMA, 326 (24), 25072518
Allergic Reactions: Severe allergic reactions are possible but uncommon
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