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18 (1), s22s30
Advanced glycation end-product accumulation and associated protein modification in type II skeletal muscle with aging
That difference sounds small until you consider that preserving 5 pounds of muscle versus losing it means a difference of about 25 extra calories burned per day, or roughly 9,000 calories per year
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The discontinuation rate due to side effects in participants with a BMI of 35 or higher was 12.1% at the 12mg dose, a figure that clinicians have called acceptable given the level of weight loss achieved
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