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3.1 Alternative nutrient-sensing mechanisms Some nutrients stimulate intestinal hormone secretion independent of taste receptors, via pathways involving other GPCR or nutrient transporters (95, 96): Stomach: Calcium-sensing receptor (CaSR) and GPRC6A detect a broad range of amino acids and calcium, promoting gastrin and somatostatin release (89, 97)

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Phase 4: Plateau Weeks 37-48 Approaching maximum effect

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opt for saline nasal rinses or intranasal corticosteroids for nasal congestion instead