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Description

Practical guidelines for the management of toxic epidermal necrolysis and StevensJohnson syndrome

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24 CaoH.ZuoC.HuangY.ZhuL.ZhaoJ.YangY.et al (2021)

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Excessive ROS directly damage tight junctions between Sertoli cells, thereby compromising bloodtestis barrier (BTB) integrity, disrupting the organization of the seminiferous epithelium, and ultimately inducing germ cell detachment and apoptosis (62)

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The reason for this effect may be that even a 90% depletion of hepatic GSH levels, as observed after an APAP overdose [91] , still leaves enough GSH (0.5-1.0 mM) as a cofactor for this enzyme activity

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Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers

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