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All statistical analyses were conducted using R software (version 4.2.3, R Foundation for Statistical Computing, Vienna, Austria)
Interestingly, a recent review of all of the known published cases of mitochondrial disease and ASD demonstrated that only about 25% had a known genetic mutation that could account for their mitochondrial disease (31)
GLP-1 receptor agonists like Wegovy and Saxenda and dual GLP-1/GIP drugs like Zepbound have produced some of the most impressive weight-loss results, Dr
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the Ministry of Science and Technology of China Major Project (XDB08020303 (H.E.X.))
However, recruitment of mini-G s to Rab5-positive EEs was reduced to an even greater extent, which can be at least partly explained by the reduced rate of internalisation with this ligand, although differences in ability to maintain GLP-1R activation once internalised could also contribute
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