Significant weight loss from tirzepatide may reduce levothyroxine requirements in some patients, necessitating TSH monitoring at baseline, after substantial weight loss, and every 6-12 months once stable
Regular exercise is also important, as it helps to burn calories and build muscle
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Postgraduate medicine
Researchers analysed the records of 23,522 adults initiating semaglutide between 2018 and 2025 at two major health systems, with two-thirds of participants having diabetes at baseline