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Overall study incorporated 100 mice (50 male, 50 female)

Beyond intracellular contacts, vesicle-mediated mitochondrial transfer can propagate damage signals across immune cells, because pyroptotic macrophage-derived microvesicles can deliver mitochondria to neutrophils and enhance NET formation and coagulopathy, and microvesicle-transferred mitochondria have been linked to cGAS-STING activation and inflammatory reprogramming in sepsis (150)

The products are exported to Europe, the United States and Southeast Asia, and the market sales are increasing year by year

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In this study, we used LOXL2 as the representative protein of the LOX family to develop and validate this new assay