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DECLARATIONS Authors contributions Developed the model, ran simulations and analyses, interpreted the findings, and contributed to the writing and editing of the manuscript: Cruikshank A, Reed MC, Nijhout HF Availability of data and materials Computer models and codes used in this paper can be obtained from the authors by request

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Targeting macrophage surface markers (CD11b, CD163, CD206) in atherosclerotic plaques in vivo can achieve macrophage-targeted drug delivery, significantly enhancing drug bioavailability and specificity (318)

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Supplements can affect oxidative stress markers, including glutathione levels

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