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Intraperitoneal injection of PMX500FI not only significantly reduced cell apoptosis in the photoreceptor layer of a mouse retinal detachment model and alleviated the inflammatory response accompanied by retinal detachment but also broadly protected the thickness of the outer nuclear layer, thereby maintaining the structural integrity and functional efficacy of the retina [322]
02 Molecular Architecture Two Peptides, Two Mechanisms, One Research Tool TB-500 and BPC-157 are structurally unrelated peptides that engage fundamentally different cellular pathways
"Questions and answers on the use of dabigatran and perspectives on the use of other new oral anticoagulants in patients with atrial fibrillation
In: Pagon RA, Adam MP, Bird TD, et al., editors
Cici, D
Regarding intracellular roGFP2-based structure-function analysis of glutaredoxins, we now showed that the GSSG-dependent oxidation of the fused glutaredoxin moiety (and not the glutathionylation of the roGFP2 moiety) is rate-limiting unless saturating GSSG concentrations are present
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