Results showed: Significant increase in skin density and thickness Measurable reduction in fine line depth (up to 35% in some cohorts) Improved skin laxity and elasticity scores Enhanced skin moisture retention These effects are largely attributed to GHK-Cus ability to stimulate fibroblast activity the cells responsible for producing collagen type I and III, elastin, and hyaluronic acid
Publisher HSS Journal Accessed Jun 27, 2026 Study type Systematic Review Limitations: A review can map the evidence base but cannot establish benefit where underlying human trials are limited
[1] In the SURMOUNT-1 clinical trial, higher doses in non-diabetic adults demonstrated significant weight loss, with participants losing approximately 15-20% of body weight over 72 weeks
This leads to a lower calorie intake, which can help with weight loss
1.18 Diagnosis, clinical presentation and treatment The diagnosis of Hashimotos thyroiditis (HT) is made based on the clinical symptoms and biochemical findings of hypothyroidism
Studies have demonstrated that collagen peptides, especially those rich in X-Hydroxyproline (X-Hyp) and X-Hydroxyproline-glycine (X-Hyp-Gly), effectively stimulate dermal collagen synthesis, enhancing skin hydration and elasticity [17]