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347 In breast cancer, Pseudomonas aeruginosa secretes the quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone (3OC), which induces ligand-independent dimerization of TRII, aberrantly activating TGF- signaling

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Because it is not FDA-approved, we dont know the risks which means taking an unregulated substance like this is a big gamble, Dr

Ryden L, Thrainsdottir I, Swedberg K

Oral metabolic franchise, a broader portfolio of oral small molecule candidates targeting metabolic disease beyond the lead GLP-1 program Recent Highlights: In May 2026, Structure reported positive end-of-Phase 2 feedback from the FDA for aleniglipron, clearing the way to begin a Phase 3 registrational program for chronic weight management in Q3 2026