The 80% increase in dentate gyrus neurogenesis and the reversal of dendritic and synaptic density loss make P21 particularly suited to the recovery phase, where the goal is not preventing further damage but restoring function
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doi: 10.1007/s00109-016-1488-y
No evidence of hormonal, hepatic, or neurotoxic adverse effects has been observed in available preclinical data
For more noticeable results, like better digestion, healing, or energy, it may take 46 weeks of consistent use
10.1007/s40121-020-00333-2 28 DuanM.LiY.LiuJ.ZhangW.DongY.HanZ.et al (2023)