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[Cut to Amy Lynn.] Amy Lynn, speaking: Patients who are starting them just need to be aware that they may have some GI side effects including nausea, vomiting, constipation or diarrhea

Preclinical and early clinical studies suggest potential roles in enhanced energy expenditure, glycemic regulation, and body composition research

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While not yet FDA-approved as a standalone agent, cagrilintide peptide therapy is being investigated for: Obesity treatment Metabolic syndrome management Adjunctive therapy for GLP-1 agonist non-responders Research in combination with emerging agents like retatrutide Note: As of 2025, cagrilintide is still considered a research compound in many jurisdictions

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On Retatrutide, where weight loss happens fast, this effect compounds quickly