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Presented for research literature review only O'Leary K (2023)
B12 is water soluble vitamin so there's no worry of overdosing them with B12
This phenomenon was initially explained by the loss of facial fat, which can lead to excess skin and profound wrinkles
Low B12 levels have been linked to mood issues like depression
In vitro experiments demonstrated that cancer-associated adipocytes upregulate the hexosamine biosynthetic pathway (HBP), leading to O-GlcNAcylation and stabilization of the YAP protein
Evidence for a disease-relevant role of lipids has come from reports that lowering blood lipid levels by diet or drug treatment may improve symptoms, including T cell-dependent autoantibody responses (116118)
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