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For side effect management, doctors can recommend dietary changes, timing adjustments, or complementary medications to reduce discomfort

doi:10.1021/acs.jproteome.3c00646 Tabb DL, McDonald WH, Yates JR

Rapid weight loss includes fat as well as bone and muscle tissue

Chronic knee pain limits physical activity, which promotes weight gain and worsens metabolic control, which drives further systemic inflammation, which accelerates joint damage, which increases pain further

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