The most common assumption on how calcium dynamics are linked to changes of synaptic efficacy is the so-called calcium-control hypothesis 27 , whereby calcium transients of large amplitude are postulated to induce LTP, while prolonged calcium transients of moderate amplitude would result in LTD, but other forms considering multiple calcium sensors have been proposed 17,28,34
Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 13620, Korea Tel: +82-31-787-7035, Fax: +82-31-787-4051, E-mail: [email protected] Copyright 2024 Korean Endocrine Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited
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No human clinical trials have been completed as of 2026
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