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[7] [8] The primary mechanism of these medications involves binding to receptors in the pancreas, brain, and gastrointestinal tract
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Spiking experiments into the plasma fraction prior to extraction showed that enzymes catalyzing the conversion of NADH to NAD+ are localized in plasma, while those affecting NAD + , NADP + and NADPH are associated with the cellular fraction (Supplementary Table 1, Sample Type 4)
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