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The peptide sequence Gly-His-Lys chelates a single Cu(II) ion through the histidine imidazole nitrogen and the deprotonated amide nitrogens of the backbone
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Pearl, D.C
Collagen types I, III, and IV go up
Possible side effects include nausea, diarrhea, vomiting, constipation, abdominal discomfort, and other digestive concerns, making professional screening and ongoing monitoring important
ClinicalTrials.gov Ipamorelin in Postoperative Ileus (NCT00672074)
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