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2 Materials and methods 2.1 Study design and participants The present study is a retrospective analysis of follow-up clinical data

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Hyperglycemia-induced mTOR upregulation leads to blood-brain barrier disruption and endothelial dysfunction, and contributes to tau hyperphosphorylation and amyloid- aggregation in Alzheimers disease (Van Skike and Galvan, 2018

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Sabag, A

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509 Clinical evidence indicates that the expression of ER stress-related proteins such as IRE1, PERK, and CHOP is reduced in SLE patients, while the levels of XBP1 and midbrain astrocyte-derived neurotrophic factor (MANF) are elevated, suggesting their potential role in disease development

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& Coulson, I

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Vitamin B-12 is essential for the maintenance of the myelin sheath, a protective covering around nerves

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