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Detectable levels of free monomers and potential toxicity exposure were reported in the selected studies on saliva, urine, and blood samples

thaliana GST protein sequences with a cutoff E -value 10 10

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Therefore, it would be crucial to understand and outline the specific contribution of each cell type MN, glia, or others to ALS, in order to strategically target them with the NRF2 activators, thereby restoring neuronal homeostasis and survival, and functional MN-glia interactions (Fig