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This selenium-containing homotetramer protein has substrate specificity for H 2 O 2 and has been classically believed to be the major H 2 O 2 reducing enzyme

(1996) Effects of vitamin B12 on performance and circadian rhythm in normal subjects

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Simultaneously, SAM levels rise due to reduced consumption by NNMT, supporting methylation reactions critical for DNA maintenance, epigenetic regulation, and neurotransmitter synthesis