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Non-enzymatic glutathionylation occur mostly during oxidative stress when GSH/GSSG is ~1 and levels of ROS are high
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Sermorelin is a 29-amino-acid synthetic copy of natural GHRH with a short 10 to 12 minute half-life
However, sermorelin tends to work in a gentler and more natural way that more closely follows the bodys normal growth hormone pulses
No published human clinical trial has established a medical use for the compound
This is one reason head-to-head binding assays dont always match head-to-head secretion experiments and why researchers occasionally get surprised when GHRP-6 outperforms GHRP-2 in certain model contexts despite lower receptor binding affinity on paper
