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Something that does wonders for one person may not do the trick for another since every individuals body is unique
At the currently approved maximum dose of 14mg, the PIONEER clinical trials showed weight loss of approximately 4-5kg (about 4-5% of body weight) over 26 weeks in patients with type 2 diabetes
Osteoporosis and Fractures : Long-term hyperthyroidism can lead to weakened bones and increased fracture risk, making travel and physical activity more hazardous [46-50]
X.ZhangZ.AnJ
10.1016/j.ajem.2024.08.039 8
While some of the trials reported a decrease in appetite as a side effect, like the ADJUNCT trials (58, 60), it should be noted that this is one of the main mechanisms of action of these drugs to achieve weight loss
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