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The results showed that in both IGF-1 treated-group, collagen was significantly increased at day 28 compared to non-IGF-1 supplementation groups (Herchenhan et al., 2015)
However, berberine interacts with drugmetabolizing enzymes and transporters and may lower blood sugar or blood pressure when combined with medications
Discuss whether GLP-1 therapy is appropriate for concurrent diabetes or obesity, potential drug interactions with DMARDs, realistic expectations about anti-inflammatory effects, and coordination between your rheumatology and endocrinology care teams
Diabetic neuropathy: cellular mechanisms as therapeutic targets
Neither compound raises major red flags on its own, and the combo doesn't seem to introduce new concerns
