PMID: 37 GregoryLGCaustonBMurdochJRMathieSAO'DonnellVThomasCPet al
Limitations: There are a few limitations to the estimates of Medicaid prescriptions and gross spending found in this analysis, including: This analysis examines the number of Medicaid prescriptions in the data and does not adjust for days supplied by each prescription
Clinical trials have shown that these medications can result in substantial and sustained weight loss when combined with lifestyle modifications, such as a balanced diet and regular exercise
Shift Melanin Production from Eumelanin to Pheomelanin: Glutathione encourages the skin to produce more pheomelanin (a lighter pigment) and less melanin (a darker pigment)
Cons: Not FDA-approved for any indication, and as of an October 2023 FDA action, ineligible for legal compounding for human use, so supply is limited to research-use-only sellers with variable purity and quality control
Standard therapeutic doses are typically used for managing Type 2 diabetes or medically supervised weight losses, and generally starts at a higher dose that gradually increases over time