Deluje sistemski u digestivnom traktu, pomae kod sindroma propusnog creva, IBS-a, greva u stomaku i Kronove bolesti
PMID: 10828840 Published Research Highlights Foundational Pharmacology 1998 First selective GHSR-1a agonist characterization Raun, Hansen, Johansen, and colleagues at Novo Nordisk reported that ipamorelin stimulated pulsatile GH secretion in rats, pigs, and dogs with selectivity over ACTH/cortisol release not seen with GHRP-6 or GHRP-2 at equivalent GH-effective doses
The findings stimulate further studies in large biobank samples to clarify whether such signatures could prove valuable for detecting pathology or follow-up of treatment effect in clinical trials
Any handling should follow institutional protocols under qualified supervision
PLoS ONE 6 , e17612 (2011)
L., Gomez Valderas, E., Dunn, J