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Inside the skin, something called oxidative stress starts happening
Ipamorelin hits the GHRP receptor and says "release GH now." CJC-1295 (no DAC) hits the GHRH receptor and says "amplify that release." When dosed together: CJC-1295 primes the pituitary and increases the available pool of GH Ipamorelin triggers the acute release of that pool The combined pulse is substantially larger than either compound generates alone research suggests synergistic effects in the range of 210x depending on baseline GH status and dosing This works because the two compounds bind to completely separate receptors
However, PPAR was downregulated in patients with NASH compared to patients with steatosis and healthy controls [75, 86], and the expression of PPAR decreased with increasing NAFLD activity score and fibrosis stage [86]
Like B12, the B vitamins in this group are powerful energy producers
however, it also reduces platelet production in some individuals (Zamani 2009)
