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The peptide increases expression of TLE1 (an NF-B inhibitor) by 762% and IL18BP (another NF-B inhibitor) by 295%, potentially inhibiting inflammatory NF-B protein activity despite increasing NF-B2 expression by 103%
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Getting out what you put in: copper in mitochondria and its impacts on human disease
Phase 3 TRIUMPH-4 (NCT05931367) reported 28.7% body weight loss at 12 mg, 26.4% at 9 mg, vs 2.1% placebo at 68 weeks
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