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Liu et al., 2018
At certain concentrations and time points, overstimulation may suppress rather than enhance melatonin output, highlighting the importance of dose, timing, and context when considering clinical protocols [1]
Starting with lower doses and gradually increasing can help minimize any gastrointestinal adjustment
The strongest responses consistently appear in connective tissue and rehabilitation-heavy environments
[8] There is a theoretical concern about stimulating angiogenesis in the setting of undiagnosed malignancy, since VEGF upregulation by GHK-Cu could theoretically support tumor vasculature
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