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Factors associated with successful continuation include proper dose escalation, proactive side effect management, dietary modifications, and realistic expectations about the transient nature of symptoms

Y., Tritschler, H

Participants Postmenopausal women, with no cardiovascular disease, liver or kidney disease, gastrointestinal disorder, including stomach ulcer or erosions, cancer, diabetes, musculoskeletal disease, and other severe chronic diseases were recruited through local advertisements

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while respiratory viral infections cause antioxidant enzyme expression/activity inhibition associated with reduced Nrf2 nuclear localization, decreased cellular levels and reduced ARE-dependent gene transcription (Komaravelli and Casola, 2014)

Because of the hypothesised abnormalities in oxidative stress and suggested links between initial inflammation, glutamate excitotoxicity and neuronal dysfunction/loss [25], our additional interest was in, GSH, glutamate and glutamine, and total choline as biomarkers of these processes