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If cost or supply issues force discontinuation, implementing the step-down approach (reducing by one dose level every 4 weeks) gives your metabolic regulatory systems the best chance of partial adaptation
In the Phase 2 obesity trial, heart-rate increases were dose-dependent, peaked around 24 weeks and then declined afterwards
Allow investigation of synergistic peptide interactions
however, if they get worse or continue, you should contact your doctor or a healthcare provider
However, starting at a full dose too often causes side effects like bloating, nausea, or constipation
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