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However, GLP-1 antagonists and GLP-1 agonists work differently: GLP-1 agonists (like Ozempic and Wegovy) mimic the GLP-1 hormone, activating its receptors to increase insulin release, suppress appetite, and slow digestion

Over the longer term, once weight stabilizes, GLP-1 medications appear to lower uric acid and reduce flare frequency, leaving patients better off