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They not only reduce weight significantly but also improve glucose control and cardiovascular outcomes, making them uniquely beneficial for patients with diabetes

It has been suggested that SGLT2-i could exert a RAS-inhibition-like effect, without being associated with a real RAS-suppression

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doi: 10.26689/jcnr.v6i1.2904 103 SchuettKKleberMEScharnaglHLorkowskiSMrzWNiessnerAet al

Table 2 also includes the tolerable upper intake level (UL) for pregnant adult women