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A May 2023 letter to the editor in the research journal Acta Pharmaceutica Sinica B (APSB) discussed these issues
O.PalmieriM.SardielloM.RodneyG
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Hum Reprod (1997) 12(6):114251
[9] A standard ladder calibrated for the average trial participant will therefore overshoot for a meaningful share of women, delivering more weight loss than they wanted along with more nausea than anyone wants
For those following plant-based diets, regular consumption of fortified foods (breakfast cereals, plant-based milk alternatives, nutritional yeast) or daily oral B12 supplements is essential
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