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GLP-1 can also be produced by neurons in central nervous system (CNS) (20, 23)
This creates a cycle where high blood sugar depletes your glutathione stores, making the cells even more vulnerable to damage
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Additionally, the regulation of ferroptosis involves other critical systems, such as the tetrahydrobiopterin (BH4)-GCH1 system (55) and the dihydrofolate reductase-reduced coenzyme Q (DHFR-CoQH 2 ) system (56, 57)
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Current research indicates that combining SGLT2 inhibitors with GLP-1 receptor agonists has shown synergistic effects (6769, 76)
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