It has been reported that the accumulation of allantoin, an intermediate product of purine metabolism, promotes ABA synthesis and participates in the response to adversity stress ( NCED1 ( Nitab4.5_0001924g0060 ) ( Supplementary Figures 9A, C )
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As an antioxidant, glutathione protects the skin from environmental damage, reducing the chances of new dark spots forming
Fruits : Avocados, watermelon, and spinach contain compounds that promote glutathione synthesis
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However, no association has yet been found with lipid peroxidation, loss of NFE2L2, and ferroptosis in human CEnCs